This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Rakesh Jain Ph.D., Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk ...

Rakesh Jain PhD, Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk ...

Depletion of CD8 T cells compromised the durability of EPN responses and reduced overall survival. These data indicate that dasatinib is an effective therapy for EPHB2-driven molecular subgroup of ...

Tumor infection with MATE-expressing oncolytic adenoviruses leads to T cell activation and tumor immunoactivation in murine tumor models, and results in a CD8-dependent therapeutic benefit.

How would you summarize your study for a lay audience?Ependymoma (EPN) is a common form of brain cancer in children, with few ...