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腾讯网
22 天
深三院结核之窗丨CRISPR/Cas系统:高效协同剪切技术在核酸检测中的应用
编者按:CRISPR/Cas系统是一种强大的基因编辑工具,其在临床中的应用已经展现出广泛的可能性和潜力,尤其是在基因治疗和 ...
生物通
1 个月
学院刘亮教授团队发现CRISPR-Cas系统具备反式切割pre-crRNA活性并开发 ...
2024年12月16日,生命科学学院刘亮教授团队在《Nucleic Acids Research》期刊上在线发表了题为“DNA target binding-induced pre-crRNA processing in type II and V CRISPR-Cas systems”的研究论文,首次揭示了靶标核酸的结合能够激活CRISPR-Cas系统效应蛋白对pre-crRNA的反式切割活性 ...
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