STAT2 天
CAR-T cells can arm other immune cells with engineered proteins to fight cancer, study says
Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting ...
Viral protein Nef enables a step toward off-the-shelf CAR T cell therapy for cancer
CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a ...
来自MSN2 天
Research Paves Way for Off-the-Shelf CAR T Cells for Cancer Treatment
CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a ...
FierceBiotech3 天
Cargo offloads CAR-T along with half of its workforce in wake of low efficacy, toxic side ...
The drug in question, called firicabtagene autoleucel or firi-cel, is an autologous CD22 CAR-T cell therapy that had been ...
VectorBuilder Powers FDA IND Approval of World’s First Umbilical Cord Blood-Derived ...
VectorBuilder's partner, Ucello, announced that its CD19-targeting umbilical cord blood-derived allogeneic CAR-T cell therapy ...
Targeted Oncology4 天
FDA Grants Orphan Drug Designation to MB-105 for R/R T-Cell Lymphoma
MB-105, a first-in-class CD5-targeted CAR T-cell therapy, received FDA orphan drug designation for relapsed/refractory T-cell ...
BioWorld3 天
Multikinase inhibitor preserves stem-like properties of CAR T cells
Although CAR T-cell treatment can lead to clinical remissions in patients with hematological malignancies, relapse rates ultimately remain high. Previous research has found that T memory stem cell ...
BioSpace3 天
Cargo Halts CAR T Trial, Lays Off 50% of Workforce in Pipeline Reset
CAR T–focused biotech Cargo Therapeutics surprised and disappointed analysts when it announced that it would discontinue a ...
pharmaphorum2 天
NICE recommends first CAR-T cell therapy on NHS in England
Yescarta – a CD19-directed genetically modified autologous T-cell immunotherapy investigated in the ZUMA-1 trial – is the first chimeric antigen receptor (CAR) T-cell therapy recommended for ...