A pathway once considered fundamental in Alzheimer’s disease is being studied intensely again, and may soon result in safer, ...

[Originally published in Synapse on January 29, 2004.] A critically ill man who is infected with TB sits at home... After a decade of moving between the Bay Area, the Midwest, and Mexico, in August of ...

Background and Purpose: Aged patients experience more cognitive dysfunction than young patients after stroke. Brain astrocytes and microglia causes excessive removal of synapses at the early stage of ...

Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic drugs in chronic asthma management has been largely underestimated.

This study uses state-of-the-art methods to label endogenous dopamine receptors in a subset of Drosophila mushroom body neuronal types. The authors report that Dop1R1 and Dop2R receptors, which have ...

Impact and progress Frontiers' impact Progress Report 2022 All progress reports ...

The authors demonstrate that both Dop1R1 and Dop2R are enriched, to differing degrees, in the axonal compartments of Kenyon cells cholinergic presynaptic inputs and in different dopamine neurons (DANs ...

Synaptic plasticity is the biological process by which specific patterns of synaptic activity result in changes in synaptic strength and is thought to contribute to learning and memory. Both pre ...