In the quiet uncertainty of an emergency department, a woman in gut-wrenching pain arrives, unable to catch a breath. Within... [Originally published in Synapse on January 12, 2006.] Last month, the ...

Although Nlgn1 and Nlgn2 are highly homologous and biochemically interact with the same extra- and intracellular proteins, Nlgn1 selectively functions in excitatory synapses whereas Nlgn2 functions in ...

2021). Cholinergics are known to influence hippocampal cognition, and one of the key pathological events in AD is a reduction in cholinergic neurotransmission (Schmeisser et al., 2012). Extracellular ...

This is an important study using a combination of optogenetics and calcium imaging to provide insight into the function of the cholinergic input to the prelimbic cortex in probabilistic spatial ...

Synchronized LTS activity required electrical synapses, but not fast chemical synapses. Tetanic stimulation of local circuitry induced effects similar to those of metabotropic agonists.

In the intricate networks of human and animal brains, decision-making is a highly complex process. While chemical synapses often take center stage, it appears they’re not the only stars of the show.

This month's cover highlights the article A novel bacterial effector protein mediates ER-LD membrane contacts to regulate host lipid droplets by Stacey D. Gilk, Rajendra Angara and Arif Sadi. The ...

The GABA (γ-aminobutyric acid)-ergic interneurons of the cerebral cortex are a diverse population of cells. Their diversity is manifested in every aspect of their phenotype, as evidenced by their ...

In 2020, Lausanne's soil was contaminated with dioxins from manufacturing processes. Cleaning is expensive and time-consuming, leaving officials unsure whether to proceed. EPFL scientists are ...