Nicotine withdrawal induces behavioral symptoms such as tremors and shaking. Suppressing striatal cholinergic interneurons or administering the muscarinic antagonist Procyclidine significantly reduces ...

Dr. Heh-In Im at the Center for Brain Disorders of the Korea Institute of Science and Technology (KIST) has identified a novel brain region and neural mechanism involved in regulating nicotine ...

Muscarinic (M) receptors involved in the airway tone regulation are as follows: M1 receptors, present on the cholinergic ganglia, with the role of facilitating neural transmission; M2 receptors ...

The US regulator has cleared the combination of muscarinic M1 and M4 agonist xanomeline ... so Cobenfy's action on cholinergic receptors offers a brand new way to treat the disorder, which affects ...

The approval has been granted to Vuity (formerly AGN-190584), a once-daily eyedrop formulation of muscarinic cholinergic agonist pilocarpine developed by AbbVie's Allergen unit that is now an ...