The BBB is made up of a luminal endothelial cell layer, a basement membrane, a perivascular space containing pericytes and perivascular macrophages, and layer of astrocytic foot processes. The ...
Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...
The resident macrophages and epithelial cells secrete chemoattractants to attract neutrophils (e.g. CXCL1 ... with a smaller proportion derived from circulation. They only cross the BBB or choroid ...
Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...
Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...
Bone-marrow-derived multipotent progenitor stromal cells — or mesenchymal stem cells (MSCs) — are the common predecessors of cells of the mesenchymal lineage, such as bone, cartilage and fat ...
eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...
This study convincingly shows that aquaporin-mediated cell migration plays a key role in blood vessel formation during zebrafish development. In particular, the paper implicates hydrostatic pressure ...
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The Price to Earnings (P/E) ratio, a key valuation measure, is calculated by dividing the stock's most recent closing price by the sum of the diluted earnings per share from continuing operations ...
This had never happened before. There is a remarkable story behind these cells; it's more than half a century old, but still relevant and current. Dr Maninder Ahluwalia, senior lecturer in ...