The reactive T cells then exit the skin, re-enter the lymphatic or vascular spaces, and recirculate or undergo the process of natural cell death. In CTCL, specific skin-homing T lymphocytes ...

Skin biopsy specimens of three lesions on her back were consistent with cutaneous T-cell lymphoma (CTCL). On physical examination, she had erythematous patches and plaques with ill-defined borders ...

The two most common types of CTCL are mycosis fungoides ... and disproportionately affect Black people. The conditions may start as patches of red or discolored itchy skin that don't go away.

T-cell skin lymphomas are more common than B-cell skin lymphomas. Cutaneous T-cell lymphoma (CTCL) occurs when a mutation causes the cell to divide too quickly and stay alive too long. The ...

The phase III placebo-controlled study conducted by Prince et al. 2 in patients with detectable CD25 on ≥20% of T cells in frozen sections of skin lesions, further defines the therapeutic ...