Cystic fibrosis causes early-life changes in the immune system, leading to frequent inflammation that persists despite CFTR modulator therapies. These therapies improve mucus clearance but do not ...

Perinatal dysfunction of innate immunity in cystic fibrosis. Science Translational Medicine , 2025; 17 (782) DOI: 10.1126/scitranslmed.adk9145 Cite This Page : ...

Learn about cystic fibrosis, a genetic disorder that affects the lungs, pancreas, and other organs, and how to treat and live with this chronic disease. 12 min read What Is Cystic Fibrosis? Cystic ...

Cystic fibrosis, a genetic disease that attacks the lungs, affects roughly 1 in 3,000 people, and cystic fibrosis-related diabetes (CFRD) is its most common complication, a rare and unique type ...

in lung function improvement with an acceptable safety profile in patients with cystic fibrosis. Researchers conducted two randomized, double-blind phase 3 trials (SKYLINE VX20-121-102 and VX20 ...

CONCLUSIONS These data support previous findings that deficiency of α 1-AT is not associated with more severe pulmonary disease in cystic fibrosis and may be associated with milder lung disease.

Purpose. The successful use of inhaled morphine to relieve dyspnea in a patient with end-stage cystic fibrosis (CF) lung disease is described. Dyspnea, the sensation of breathlessness or labored ...

In December, the FDA approved Vertex’s vanzacaftor, tezacaftor and deutivacaftor (Alyftrek) for the treatment of cystic fibrosis in patients with at least one F508del mutation or another ...

CMTX-101 is under clinical development by Clarametyx Biosciences and currently in Phase II for Cystic Fibrosis. According to GlobalData, Phase II drugs for Cystic Fibrosis have a 31% phase transition ...

NEW research highlights a critical yet often overlooked connection: poor sleep quality significantly increases the risk of malnutrition among adolescents with cystic fibrosis (CF). The findings, drawn ...

A Melbourne teenager who is fighting for her life has just been separated from her brother - and it's the only thing that might keep her alive. Claudia Coll, 18, was born with cystic fibrosis and has ...

erasmusmc.nl Background Cystic fibrosis (CF) lung disease is characterised by progressive airway wall thickening and widening. We aimed to validate an artificial intelligence-based algorithm to assess ...