Feb. 10, 2025 — Evolution is traditionally associated with a process of increasing complexity and gaining new genes. However, the explosion of the genomic era shows that gene loss and ...

Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

One way to differentiate them is to detect specific molecules on these cells that act as markers. Some aspects of the disease can be readily seen by studying individual cells and their appearance, ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

The Department of Government Efficiency (DOGE) announced Wednesday that the Social Security Administration’s move to terminate a contract dealing with the "Gender X" marker on public-facing ...

Background: Programmed death 1 (PD-1) and the ligand of PD-1 (PD-L1) are central targets for immune-checkpoint therapy (ICT) blocking immune evasion-related pathways elicited by tumor cells. A number ...

PTEN and ARID1A haploinsufficiency is also observed at the molecular level with changes in downstream effectors, increased cell proliferation and reduction of immune cell infiltration. We have ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...