particularly following an insult Selective expression of mutant proteins associated with neurodegenerative diseases in astrocytes is sufficient to cause neuronal damage Mutations in the astrocyte ...

The transfer consequently elevated mitochondrial membrane potential in the recipient cells. By introducing Alexander disease (AxD)-associated hotspot mutations (R79C, R239C) into GFAP gene of hPSCs ...

New research found significant changes in brain biomarkers linked to Alzheimer's disease in those who had contracted the ...

Similarly, UPR-activated astrocytes exhibit an increase of inflammatory response but a decrease ... Therefore, it is urgent to identify novel therapeutic targets to modulate disease-associated ...

COVID-19, even in mild cases, is linked to changes in Alzheimer’s disease-related brain biomarkers comparable to four years ...

Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia ...

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ... Major Cause of Inflammatory ...