They find that individuals who carry a high burden of expanded repeats in their DNA have a more than three-fold increased risk for Alzheimer’s disease. Rabah et al. discover an astrocyte-to ...
particularly following an insult Selective expression of mutant proteins associated with neurodegenerative diseases in astrocytes is sufficient to cause neuronal damage Mutations in the astrocyte ...
and Parkinson's disease (PD) have been developed, and these models are reviewed later in this article. Some examples of mouse models in which astrocyte protein function is altered are detailed in ...
SARS-CoV-2, which causes the Coronavirus Disease 2019 (COVID-19) pandemic, has a brain neurotropism through binding to the receptor angiotensin-converting enzyme 2 expressed by neurones and glial ...
June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ... Major Cause of Inflammatory ...
It is believed that chronic signaling from these cells affects the homeostatic network of neuronal and non-neuronal cells to an extent to destabilize this harmonious milieu in neurodegenerative ...