Synaptic plasticity is the biological process by which specific patterns of synaptic activity result in changes in synaptic strength and is thought to contribute to learning and memory.

16). We tested the hypothesis that mutant APP causes age-dependent learning impairment through disruption of synaptic plasticity. Figure 2: LTP is impaired in the dentate gyrus in aged APP 695 SWE ...

Here, we build a continuous attractor neural network with synaptic short-term plasticity (STP) to explore the neural mechanism of the serial position effect. Using a delay recall task, our model ...

Institute for Advanced Materials and Guangdong Provincial Key Laboratory of Optical Information Materials and Technology, South China Academy of Advanced Optoelectronics, South China Normal University ...

Faculty of Pharmacy and Research and Innovation Hub, Alamein International University, Alamein, Matrouh 51718, Egypt Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria ...

The current human tissue-based study provides convincing evidence correlating hippocampal expressions of RNA guanine-rich G-quadruplexes with aging and with Alzheimer's Disease presence and severity.