Locations of drug transporters Various drug ... across enterocytes into the portal circulation. This process repeats itself and is termed enterohepatic recycling. Some drugs, such as oral ...

The pK a, log P, and intestinal transport mechanisms ... across enterocytes into the portal circulation. This process repeats itself and is termed enterohepatic recycling. Some drugs, such as ...

As the liver is the only site of bile acid synthesis, more studies on the bile acid profile of liver tissues are needed to fully reveal the role of bile acids in liver fibrosis in terms of its ...

Acute kidney injury (AKI) is a common critical clinical disease that is linked to significant morbidity, recurrence, and mortality. It is characterized by a fast and prolonged loss in renal function ...

Transporters are integral-membrane proteins that form a pore within the plasma membrane to allow passage of various types of molecules, including ions, small molecules and proteins. Transporters ...

Similarly, BAs enterohepatic circulation and host genetic factors can affect their utility as gut health ... funded by the Austrian Ministry for Transport, Innovation and Technology, the Austrian ...

The integrative physiology of the left ventricle and systemic circulation is fundamental to our understanding of advanced heart failure and cardiogenic shock. In simplest terms, any increase in aortic ...

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Cassidy is an updates editor whose main responsibility is to write and edit articles on a range of home improvement topics. Her passion for lifestyle writing began with her editorial ...

Fibroblast growth factors (FGFs) signal through FGF receptor tyrosine kinases to regulate a wide range of biological processes during development and adulthood. FGF receptors (FGFRs) are involved ...

The Saint Louis University Department of Pharmacology and Physiology is made up of highly accomplished faculty and scholars who are widely recognized with awards, appointments to national committees ...