The focus of the presentation will be on the subgroup of patients who have received 100mg bezuclastinib for at least 48 weeks to highlight the symptomatic benefits of long-term use.

A live webcast can be accessed on the Investors & Media page of Cogent’s website at https://investors.cogentbio.com/events. A replay will be available approximately two hours after the completion of ...

The tyrosine kinase inhibitor imatinib targets the human KIT receptor and the platelet-derived growth factor receptor-α. This drug exhibits impressive antitumor effects against GIST and has ...

From left to right: The 2025 home shirts of Super League clubs Hull KR, Leeds Rhinos, Hull FC and Castleford Tigers - Image Credits: Hull KR, Hull FC, OXEN Sports It’s that time of the year again when ...

The first 2 criteria are associated with imatinib's efficacy in CML (BCR-ABL fusion), GIST (KIT or PDGFRA mutation), and HES (FIP1L1-PDGFRA fusion). The information we have for SCLC in regard to ...

Amid fresh controversy over the Board of Control for Cricket in India's alleged refusal to have 'Pakistan' printed on the team's Champions Trophy kits as part of the tournament logo, the Indian ...

GIST typically presents in the GI tract with 80% of cases driven by mutations in the KIT gene that lead to the growth, proliferation, and survival of tumor cells (primary or activating mutations).

Department of Chemistry and Chemical Biology, TU Dortmund University and Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW), Otto-Hahn-Strasse 4a, Dortmund 44227, ...

Summary: A new study has uncovered a direct link between somatic mutations and epigenetic modifications, challenging established views on aging. Researchers found that random genetic mutations drive ...

Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations and predictable epigenetic modifications.

Though unconfirmed by the club, Footy Headlines reports that Charlotte's new away kit for the 2025 season will feature black, replacing the purple used for the past two years. The design will ...

Health authorities and researchers are closely examining the mutations found in the virus extracted from the 65-year-old man, who was infected through contact with backyard birds contaminated by ...