Glycolysis is a central metabolic pathway by which cells obtain energy from sugar. Cancer cells in particular have long been thought to depend on the energy obtained through glycolysis, a phenomenon ...

If it can inhibit the activity of glycolysis-related enzymes and control the energy metabolism of tumor, it can be targeted for the treatment of malignant tumor. The target proteins phosphoglycerate ...

The enzyme aconitate decarboxylase 1 (Acod1 ... differentiation by inhibiting succinate dehydrogenase-dependent production of reactive oxygen species and Hif1α-mediated induction of aerobic glycolysis ...

Even when glycolysis is blocked, they survive by obtaining their energy through the respiratory chain. This makes the results published by Almut Schulze and colleagues from the German Cancer Research ...

Enzymes are crucial to life ... So, we have a way to go on the data front, but we'll get there. This is the first step." ...

However, when the researchers blocked an “earlier” step in glycolysis, the enzyme glucose-6-phosphate isomerase, this had no effect on the growth of the cancer cells. “The glycolytic enzyme ...

An increasing amount of evidence indicates that aerobic glycolysis performs a significant function in the progression and ... and decreased the expression of glycolytic enzymes. The implementation of ...

Elevated liver enzymes can occur for many reasons. Most often, elevated liver enzymes are temporary and resolve on their own without treatment. Occasionally, elevated liver enzymes require additional ...