For example, the Golgi has been linked to cell migration, cell division, cell growth and apoptosis, as indicated by the findings showing that these processes are accompanied by the fragmentation of ...

Golgi phosphoprotein 73 (GP73, also termed as GOLM1 or GOLPH2) is a glycosylated protein residing on cis-Golgi cisternae and highly expressed in various types of cancer tissues. Since GP73 is a ...

Schecterson LC, Hudson MP, Ko M, Philippidou P, Akmentin W, Wiley J, Rosenblum E, Chao MV, Halegoua S, Bothwell M (2010). Trk activation in the secretory pathway promotes Golgi fragmentation. Mol Cell ...

ER–Golgi transport: overexpression of LRRK2 may promote the improper polymerization of tubulin in neurons, which might cause the fragmentation of the Golgi apparatus and exacerbate α-syn ...

Ethereum Layer-2 networks face reduced fragmentation but struggle with interoperability. Experts highlight tools and frameworks enhancing cross-chain solutions for users and developers. Ethereum’s ...

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug ...

The inactivation of programmed cell death has profound effects not only on the development but also on the overall integrity of multicellular organisms. Beside developmental abnormalities, it may lead ...

Apoptosis and autophagy constitute the two self-destructive processes by which supernumerary, damaged or aged cells and organelles are eliminated. Beyond this homeostatic function, autophagy is ...

This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...