No writing assistance was utilized in the production of this manuscript. Dolutegravir is an HIV integrase strand transfer inhibitor (INSTI) that does not require pharmacokinetic boosting ...

Real-world analyses have confirmed the efficacy of the 2-drug regimen of dolutegravir and lamivudine in treating HIV, confirming phase 3 testing results. HIV causes immunosuppression because the ...

The four main classes, which most people are treated with, target one of three viral proteins which control HIV’s lifecycle: reverse transcriptase, integrase and protease ... The HIV capsid is a ...

when ViiV – a joint venture majority owned by GlaxoSmithKline alongside Pfizer and Shionogi – accused Gilead of infringing its patents on HIV integrase inhibitor dolutegravir. The dispute ...