Even today, most biophysical spiking models are based on the H-H equations. What have computational neuroscientists learned from Hodgkin and Huxley? First, they chose the right model system.

Hence, researchers often simulate the brain as a network of coupled neural masses, each described by a mean-field model. These models capture the essential features of neuronal populations while ...

Models can provide experimentally testable predictions and a level of insight not otherwise achievable. A classic example is the Hodgkin-Huxley model for the generation of axon potentials in the ...

(This concept and velocity equation came from the historic study of action potentials in the squid giant axon by Alan Hodgkin and Andrew Huxley in the 1940s-50s, partly at MBL.) However ...