The hypothalamus is the main area in the brain ... there are orexigenic coexpressing neuropeptide Y/Agouti gene-related protein (NPY/AgRP) and anorexigenic pro-opiomelanocortin (POMC)/cocaine ...

The study presents compelling evidence that the melanocortin system originating in the arcuate nucleus of the hypothalamus plays a crucial role in puberty onset, representing a significant advance in ...

Hunger is an ancestral and evolutionary survival instinct; its importance is evident in the complex and redundant pathways involving all five senses that regulate it. 1,2 Historically, when humans ...

Alcohol also suppresses pro-opiomelanocortin (POMC) neurons, a type of cell in the hypothalamus which reduce appetite, caused by the decrease in leptin and insulin (as mentioned above). On the ...

There are also leptin receptors in MCH neurons of the lateral hypothalamus. Genetic and physiological studies have shown that NPY, AgRP, α-melanocyte-stimulating hormone (α-MSH, a POMC-derived ...

To investigate the hypothalamus as a potential key target of 17α-estradiol’s effects on life ... ukb-e-30800_CSA). Interestingly, QRFP, IGF1, AGRP, TAC4, GRP, CLU, BNF, PCSK7, PACAP, ANP, TAC3, CRH, ...

4,5 These ghrelin-containing neurons send efferent fibers to neurons that contain neuropeptide Y (NPY) and agouti-related protein (AgRP)—NPY/AgRP neurons—and might stimulate the release of ...