It was filtered to remove the precipitated product. Synthesis of methyl 4-(5-chloro-1H-benzo[d]imidazole-2-yl) benzoate (2): 4-Chlorobenzene-1,2-diamine (0.022 mol) was dissolved in DMF, and sodium ...

Therefore, N,N′-carbonyldiimidazole was used in the current study to react with carboxylic acid to obtain a highly active acyl imidazole. An amine was added directly, and the mixture was reacted for ...

Recently, our group and some researchers have utilized machine learning to expedite the process of material discovery and achieve accurate synthesis of high-performance AEMs. In this Account, we ...

Key Laboratory of Intelligent Supramolecular Chemistry at the University of Yunnan Province, National and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials ...

CYP51 (Erg11) belongs to the cytochrome P450 monooxygenase (CYP) superfamily and mediates a crucial step of the synthesis of ergosterol, which is a fungal-specific sterol. It is also the target of ...

The column was washed with increasing concentrations of imidazole, and the atACS protein was eluted with 0.2 M imidazole ... whereas Peak B supports the catalysis of acetyl-CoA synthesis ...

"Although the α-D-ribofuranoside structure is frequently found in natural products, there have been fewer reports of the synthesis of α-D-ribofuranosides than of the β-anomers. Thus, the ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...