A revolutionary approach to immune therapy has emerged: engineered immune cells that protect healthy tissue without ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use the insulin ...

Researchers at IISc Bengaluru discover potential drug-free treatment for diabetes by enhancing beta-cell function with small molecules.

These ‘insulin-producing cells’, or IPCs, play the same role as the beta cells that create insulin in the human pancreas. As fruit flies can easily be genetically manipulated, IPCs have drawn ...

MHH team aims to intervene in the autoimmune process and stop the destruction of insulin-producing beta cells in the pancreas ...

Diabetes is a common, lifelong condition that occurs when the pancreas doesn't produce enough insulin, or when the body is ...

Although it is clear that beta cell dysfunction is the main factor responsible for the progression to hyperglycemia, insulin resistance predates beta cell dysfunction, and reversibility of insulin ...

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

Last year, CellTrans claimed the first FDA approval for a cell therapy for type 1 diabetes, Lantidra (donislecel) consisting of insulin-producing islet beta cells taken from deceased donors.