When the lateral collateral ligament is completely torn, a surgical procedure is typically recommended to either repair or reconstruct the ligament. When the ligament is torn at the location of the ...

Examining the nature and origin of human intelligence and the intersection with machine intelligence in the past, present and ...

An expansion of a hexanucleotide repeat in the C9ORF72 gene can cause ALS. Here, the authors develop a high-fidelity RNA-targeting CRISPR system to suppress the repeat RNA expressed from the ...

The cerebellum plays a major role in balance, motor control and sensorimotor integration, but also in cognition, language, and emotional regulation. Several neuropsychiatric disorders such as ...

It has long been assumed that neocortical interneurons belong to different classes 1, with the variability in their features within a class being much smaller than the differences across classes.

1982; Matthews, 2001); (ii) Synaptic modification by way of Hebbian-type learning, including the two biological mechanisms of long-term potentiation (LTP) and long-term depression (LTD) (Artola and ...

Hence, researchers often simulate the brain as a network of coupled neural masses, each described by a mean-field model. These models capture the essential features of neuronal populations while ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. AUTS2 syndrome patients often exhibit ...

This study examined the important question of how neurons code temporal information across the hippocampus, dorsal striatum, and orbitofrontal cortex. Using a behavioral task in the rat that requires ...

Objectives To evaluate the current evidence for the efficacy of corticosteroid injection and non-electrotherapeutic physiotherapy compared with control for treating lateral epicondylitis. Design ...

The brain is in a constant state of dynamic change, for example switching between cognitive and behavioural tasks, and between wakefulness and sleep. The brains of people with epilepsy have additional ...