Background: Ischemic white matter injury leads to long-term neurological deficits and lacks effective medication. Accumulating evidence suggests that microglia contribute to pro-remyelinating after ...

Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

Microglia, macrophage counts, and TNF-α expression were evaluated using flow cytometry. Long-term behavioral tests included the Barnes maze (days 7 and 30), novel object recognition (day 10), and ...

CSF1R inhibitors have been used extensively to deplete microglia in the healthy and diseased brain. In this study, we demonstrated sex-dependent differences in the microglial response to the CSF1R ...

Transcriptomic and flow cytometry analysis revealed sex-specific differences in the remaining microglia population, with female microglia upregulating autophagy and proteostasis pathways while ...

Microglia, the brain's immune cells, exhibit altered gene expression and a weakened immune response as they age, potentially contributing to neurological disorders like Alzheimer's and Parkinson's.

In his landmark 1990 book Flow, psychologist Mihaly Csikszentmihalyi described flow as “a state in which people are so involved in an activity that nothing else seems to matter; the experience ...

Cell culture and flow cytometry gauge SORL1 maturation, cell surface expression ... SORL1 also delivers critical synaptic receptors, such as GLUA1, to the neuronal surface. Yet, SORL1 gets plenty busy ...

Last year I reviewed the Insta360 Flow Pro, the first iPhone gimbal to support Apple’s DockKit technology for seamless integration with the iPhone. Insta360 is now introducing Flow 2 Pro ...

While I wouldn’t suggest buyers of the original Flow Pro chuck out their gimbal in favor of this model, the Insta360 Flow 2 Pro does represent an upgrade on what was already one of the best ...