2020). Microglia can also play a significant neuroprotective role during excitotoxic events. When challenged with glutamate, tri-cultures have significantly less neuronal cell loss compared to ...

The cylinder test and grid-walking test were performed to evaluate functional recovery. The potential molecular mechanisms of excitatory neuronal activation on microglia-mediated synaptic pruning ...

Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...

点击蓝字关注我们神经性疼痛作为最顽固的慢性疼痛类型，在女性中的患病率显著高于男性。性别依赖的神经免疫机制是神经损伤引起的异常性疼痛的基础。动物实验表明小胶质细胞介导雄性慢性疼痛的发生过程，而适应性免疫系统介导雌性疼痛反应。Panx ...

Summary: Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also contribute to neurodegenerative diseases if overactive. New research ...

Aerobic exercise may significantly reduce Alzheimer's disease markers, with studies showing up to 76% decreases in harmful ...

Xenon gas, currently used in medicine as an anesthetic and neuroprotective agent for treating brain injuries, showed ...

Microglia are the cells on cleanup duty throughout the central nervous system ... by increasing amyloid and phosphorylated tau protein production and contributing to neuron degeneration and death.