and GWAS data are expected to increase our understanding of these regions. Autosomal recessive forms of inheritance are different from X-linked inheritance. When using whole exome sequences (WES), we ...

Background SLE is a systemic autoimmune disease with a large number of common risk gene variants, but several rare gene ...

PMID or link refers to the pubmed.gov identifier (PMID) for the publication or publications establishing the gene as a monogenic route to lupus or a review of several publications. Supplementary Table ...

Fields as diverse as human genetics and sociology are increasingly using polygenic scores based on genome-wide association studies (GWAS) for phenotypic prediction. However, recent work has shown that ...

Within the prior 24 months, I have had a financial relationship with a company producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients: Receive the the ...

Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN. (M.R.A., D.G.H.) Division of Cardiovascular Medicine ...

These variants are usually discovered in genome wide association studies (GWAS). In a GWAS, hundreds of thousands or millions of SNPs are genotyped with the aim of finding variants that are present at ...

Filtered WES data were reviewed for genes underlying Mendelian disorders and loci reported in EDS linkage, transcriptome and genome-wide association studies (GWAS). A genetic burden analysis (Minor ...

Correspondence to Dr Séverine Vermeire, Department of Chronic Diseases, Metabolism and Ageing - TARGID, KU Leuven, Leuven B-3000, Belgium; severine.vermeire{at}uzleuven.be IBD is a complex ...

The purpose of the course is to introduce the use of various Omics technologies, which aim to collectively characterize pools of biological molecules in a single experiment. The focus is Omics ...