Introduction: Metastatic rhabdomyosarcoma (RMS) is a challenging tumor entity that evades conventional treatments and endogenous antitumor immune responses, highlighting the need for novel therapeutic ...

Collaboration to explore the immunoregulation of NK and T cells within the tumor microenvironment (TME) by CAPTN-3, with the ...

Here, we report that TRAIL is constitutively expressed on murine natural killer (NK) cells in the liver and plays a substantial role in suppressing tumor metastasis. Freshly isolated NK cells ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

Tumor-Secreted Protein May Hold the Key to Better ... the most common and incurable type of adult brain ... NK Cells Expressing Interleukin-21 Show Promising Antitumor Activity in Glioblastoma ...

Aims: This research endeavor seeks to formulate a predictive tool specifically designed for PDAC based on NK cell-related long non-coding RNA (lncRNA), revealing new molecular subtypes of PDAC to ...

An approach using engineered small extracellular vesicles from NK cells to DR5 could be a promising strategy for solid tumors ...

Researchers identify target to enhance NK cell function for liver cancer therapy in Korea New insights into immune cell dynamics could lead to innovative therapies for cancer in Korea.

NK-derived sEVs are good at infiltrating tumors and typically contain molecules that are toxic to tumor cells. Xu and his team engineered the NK sEVs so that they have an antibody fragment that ...

Fate Therapeutics uses iPSC and gene editing to offer scalable off-the-shelf therapies. Read more to see why I rate FATE ...

FT596 has features that allow the CAR-NK cells to target the cancer in two different ways to avoid tumor resistance, compared with standard CAR-T cell therapy, which only targets the cancer cells ...