Researchers used mice with nine different genetic backgrounds to identify factors influencing eye aging, paving the way for eye-based diagnostics for neurodegenerative diseases.

Vision changes are an inevitable part of aging, but why are some more susceptible to age-related eye diseases and why do some individuals experience more severe decline than others?

Glaucoma is a group of eye diseases that damage the optic nerve, which connects the eye to the brain. In most cases, glaucoma is caused by high pressure inside the eye. However, normal-tension ...

Scientists restore a key Alzheimer’s pathway, revealing a potential new treatment by targeting harmful oxysterol buildup.

Scientists from Brigham and Women’s Hospital have now identified a new protein that may contribute to the disease.

The findings suggest that vascular dysfunction could be an early driver in neurodegenerative disorders rather than being ...

A disintegrin and metalloproteinase 17 (ADAM-17) has multiple pathophysiological functions in Alzheimer's disease (AD). However, the clinical relevance of ADAM-17 in AD is not clear yet.This study ...

The preliminary data presented in this manuscript seem valuable. The data are currently incomplete and there are numerous technical concerns, some of which may arise from insufficient description of ...

Researchers combined animal models, human brain tissue, and molecular analysis to uncover a connection between Alzheimer's ...

A study reveals that traumatic brain injury alters the small vessels in the brain, resulting in an accumulation of amyloid ...