The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

Kymera Therapeutics, Inc., 500 North Beacon Street, Watertown, Massachusetts. *Corresponding Author: Yogesh K. Chutake, Kymera Therapeutics, Inc., 500 North Beacon ...

Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, USA Department of Biomedical Sciences, Seoul National University College of ...

THE Department of Agriculture (DA) on Thursday said it will likely declare a food security emergency for rice as prices of the staple grain remain stubbornly high.

从机制上讲，Stub1通过HSPA8促进ASFV p72的多泛素化。多泛素化的p72随后与自噬受体SQSTM1 / p62相互作用，导致其通过选择性自噬途径降解。这些发现揭示了p72通过自噬降解的机制，并为ASFV衣壳解体过程提供了新的见解。 非洲猪瘟（ASF）是由非洲猪瘟病毒（ASFV ...

Uniquely, only in the nucleus does unfolded protein activate a robust p53-driven transcriptional response and a transient p53-independent cell cycle delay. These studies highlight the distinct effects ...

The primary node molecules in the cell signaling network in cancer tissues are maladjusted and mutated in comparison to normal tissues, which promotes the occurrence and progression of cancer.

Oral cancer is a highly malignant disease characterized by recurrence, metastasis, and poor prognosis. Autophagy, a catabolic process induced under stress conditions, has been shown to play a dual ...