The pharmacological reestablishment of calreticulin exposure may ameliorate the efficacy of chemotherapy, and the development of non-toxic PP1-inhibitory molecules that can induce calreticulin ...

This confirmed that an unfortunate mistake was made during the figure assembly process where the gamma-H2AX immunoblot for the PP4C/PP1 condition (panel A) was duplicated in panel B. The updated ...

3, 2024 — A research group has discovered that in mammals, a protein kinase A (PKA) promotes wakefulness, while protein phosphatase 1 (PP1) and calcineurin promote sleep. This study revealed ...

The adeno-associated virus (AAV) based therapy delivers a gene coding for a therapeutic protein, known as inhibitor-1 or I-1, which blocks the activity of protein phosphatase 1 (PP1), an enzyme ...

3, 2024 — A research group has discovered that in mammals, a protein kinase A (PKA) promotes wakefulness, while protein phosphatase 1 (PP1) and calcineurin promote sleep. This study revealed ...

An Fc receptor for human immunoglobulin G is located within the tegument, along with the serine/threonine protein phosphatase PP1 and the host cell-derived phosphatase PP2A (ref. 6). The viral ...

As they often do, the Buffalo Sabres practiced their power play Tuesday at KeyBank Center. In December, there was little continuity from one session to the next. Coach Lindy Ruff continued ...

Mutations in the genes for the phosphatase laforin or the E3 ubiquitin ligase malin can cause LD. By depleting PTG, an activator of the glycogen chain-elongating enzyme glycogen synthase (GYS1), in ...

1 Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China 2 Shanghai Frontiers Science Center for Drug Target ...

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1 Obstetrics and Prenatal Medicine, Department of Gynecology and Obstetrics, University Hospital Frankfurt, J. W. Goethe-University, Frankfurt, Germany 2 Center for Internal Medicine, Department of ...