A common genetic pathway may account for increased risk for atherosclerotic disease in patients with chronic widespread musculoskeletal pain. Chronic widespread pain (CWP) and atherosclerotic disease ...

How does your brain know when you feel pain? How does it know the difference between the soft touch of a feather and a needle prick? And, how does that information get to your body in time to respond?

Now, after 25 years of research, scientists at Vertex Pharmaceuticals figured out how to block this same pain pathway with suzetrigine, leading to a new pain medication for the FDA to approve.

Scientists have developed targeted medications that affect specific pain pathways while minimizing systemic effects. These precision formulations reduce side effects while providing more ...

Studies shed light on pain perception, placebo effect pathways, and how human stem cells can be used to model pain. Sneha Khedkar is an Assistant Editor at The Scientist. She has a Master's degree in ...

After developing chronic pain, I started looking into what scientists do — and still don’t — understand about the disease. Here is what I learned. By Jennifer Kahn Most of us don’t think ...

NSAIDs are among the most common pain relievers in the world. And lately, they're among the most controversial. Find out what these anti-inflammatory pills actually do inside your body.

What Is SI Joint Pain? Injury, pregnancy, or uneven movement in your pelvis can cause low back, butt, and leg pain that's often worse after you've been sitting for a while. This may be because ...

Anxiety can sometimes cause physical symptoms like chest pain and pressure. But because these symptoms can also indicate heart conditions, it’s important to get an accurate diagnosis.

Ear pain has numerous causes. Most are treatable, though some are serious. Conditions responsible for ear pain can strike anyone at any age. If you begin to develop ear pain, it's essential to see a ...