The US Food and Drug Administration (FDA) will soon decide on whether to expand the label of MSD’s Welireg (belzutifan) to include its use for the treatment of the rare cancer pheochromocytoma and ...

Immune cells rely on cell-cell communication to specify and fine-tune their responses. They express an extensive network of cell communication modes, including a vast repertoire of cell surface and ...

PPGL is a group of rare neuroendocrine tumours originating from adrenal gland tissue or paraganglia. These tumours are often challenging to treat in advanced stages, and current therapeutic ...

Closely related tumors of extra-adrenal sympathetic and parasympathetic paraganglia are classified as extra-adrenal paragangliomas. Although arbitrary, this nomenclature serves to emphasize the ...

Neuroendocrine differentiation (NED) is a term referring to certain cancers that display a prominent neuroendocrine (NE) cell population on histopathologic examination. Although the definition has ...

The presented patient had recurrent pheochromocytomas, in addition to a nonfunctioning incidentaloma; his mother has a history of multiple HNPs. Familial involvement and multiple tumors within a ...