Both the pitavastatin molecule and the lactone metabolite undergo very little metabolism by CYP3A4 and, therefore, unlike some other statins, does not interact with CYP3A4 substrates. Pitavastatin ...
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New mechanism found in statin therapy's heart benefits for HIVThe work is a secondary analysis of the Phase III Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE), which demonstrated that the cholesterol-lowering medication pitavastatin reduced ...
[13] In clinical studies, pitavastatin consistently produces a marked and sustained increase in HDL-C concentrations. Indeed, pitavastatin's ability to elevate HDL-C levels is one factor ...
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