Drug metabolism is divided into phase 1 and phase 2 reactions ... for predicting the impact of dosage regimen alterations on target seven-day lumefantrine plasma concentrations involving the CYP2B6. A ...
The process of target identification between ... will be important for any company developing novel drugs that target cancer metabolism. “This requires more vision from drug companies, who ...
14 in Nature Metabolism, also challenges long-held ... and are continuing to study their implications on the entire drug manufacturing process. "Our work has the potential to make drug production ...
The key process of balance among glycolysis, TCA and other pathways of the glucose metabolism in tumor remains unclear, as it is the essential mechanism of Warburg effect. In addition, it should be ...
Understanding how tumors change their metabolism to resist treatments is a growing focus in cancer research. As cancer cells adapt to therapies, their ...
During protein production, CHO cells release lactic acid as a byproduct of their metabolism ... their implications on the entire drug manufacturing process. "Our work has the potential to make ...