The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

Propranolol reduces Parkinson’s tremor and motor cortex activity, suggesting a new therapeutic approach beyond stress ...

The mechanism of action underlying ketamine’s rapid antidepressant effects in patients with depression, both suffering from major depressive disorder (MDD) and bipolar disorder (BD), including ...

Propranolol's protective effect was found to be more pronounced in women with migraines without aura and for ischemic stroke. For patients with migraine, the clinical benefits of propranolol, a ...

Propranolol, a beta blocker medication used for treating high blood pressure and preventing migraines, may lower ischemic stroke risk in women who experience migraines frequently. A medication ...

Women taking propranolol for migraine prevention may reap reduced risk of ischemic stroke as an added benefit, according to data presented as an abstract this week at the International Stroke ...

Propranolol is a very promising new medical therapy, but its mechanism of action is unknown and published data are limited to case reports. Possible future directions of treatment include targeted ...

Canonically, the metabolic depletion of tryptophan and/or the accumulation of kynurenine is the mechanism that defines how immunosuppressive IDO inhibits immune cell effector functions and/or ...

Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...

Even though there are indications of the health-promoting and cell-protective properties of ergothioneine, the underlying mechanism of action was previously unknown. "Our analyses now finally ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

2025 has a full slate of action movies, each more exciting than the next. The genre has never been more popular, and luckily for audiences, creatives and producers know it. Action is also ...