In the T cell, cAMP is known as a potent negative regulator, which dampens T-cell immune function through the cAMP/protein kinase A (PKA) signaling pathway. Indeed, the cAMP/type I PKA/Csk/Lck ...

Receptor tyrosine kinases function at the beginning of a number of signal transduction cascades, whereas nonreceptor tyrosine kinases and serine/threonine protein kinases function throughout ...

Ideaya is financially strong, with $1.2 billion in cash reserves, sufficient to fund operations into at least 2028. Click ...

What is ALPK2, and how can it help treat heart failure? Researchers have found that this heart-specific enzyme may prevent ...

Researchers from the Nagoya University Graduate School of Medicine identified an enzyme, alpha-kinase 2 (ALPK2) that is ...

A "pocket" on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct ...

To further probe Mediator kinase function, we completed cytokine screens and metabolomics experiments. Cytokines are master regulators of inflammatory responses; by screening 105 different cytokine ...

This article reviews the biological characteristics of the UL51 protein and its functions in herpesviruses, including participating in the maintenance of the viral assembly complex (cVAC) during viral ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...