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压电定向的中性粒细胞胞外陷阱在流感病毒感染期间调节巨噬细胞分化
中性粒细胞和巨噬细胞是抵御病原体微生物感染的重要免疫细胞。在病原体入侵时,中性粒细胞率先被招募到感染部位,通过吞噬、产生活性氧(ROS)等方式发挥抗菌作用,同时其释放的 NETs 也备受关注。NETs 由双链 DNA、组蛋白和非组蛋白蛋白质组成,在调节免疫反应中发挥重要作用。巨噬细胞则可分化为 M1 和 M2 两种类型,M1 型巨噬细胞分泌促炎细胞因子,增强免疫反应;M2 ...
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