The platform enables direct, unbiased genome-wide identification and quantification of the exact position of double strand DNA breaks in edited cells.

引言与DNA不同，RNA不仅是基因表达的中介，还是细胞内多种复杂生物学过程的关键调控因子。近年来，RNA编辑作为RNA分子的一种天然修饰过程，引起了科学界广泛的兴趣。RNA编辑技术不仅能够精确调控基因表达，还为治疗各种遗传性疾病和复杂疾病提供了新的可 ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “Acquired RUFY1-RET rearrangement as a ...

Alida Biosciences (AlidaBio), an innovator in epigenomic research tools, today announced the full commercial launch of its EpiPlextm platform, the first to concurrently detect and quantify multiple ...

A multi-institutional study has identified one of the allergens responsible for eosinophilic esophagitis (EoE), an inflammatory disease of the esophagus. This is the first time one of the allergens ...

A new computational tool could help researchers identify promising drug combinations for treating cancer, according to a new ...

Scientists have developed retriever, a computational tool that extracts disease-specific drug response signatures to predict the best combinations for cancer treatment.

Researchers studying gene expression have access to vast amounts of data from cells or tissues. This is thanks to advances in ...

A multi-institutional study is the first to identify one of the allergens responsible for eosinophilic esophagitis (EoE), an inflammatory disease of the esophagus. This is the first time one of the ...