Neurological diseases are highly heterogeneous; however, they share a common pathogenesis, that is, the aberrant accumulation of misfolded/unfolded proteins within the endoplasmic reticulum (ER).

It is well known that inter-organellar communications play important roles in maintaining cellular homeostasis in response to environmental stresses. The endoplasmic reticulum (ER), extending ...

Dynamic changes in the structural characteristics of the postsynaptic membrane and, in particular, of dendritic spines have been a topic of great interest over the last decade (reviewed in refs.

Evidence for a final common pathway for disorders of the myocardium (pages 246 and 320–330). These studies further our understanding of the heart in health and disease, particularly in the ...