Additionally, Phosphorylated eIF2α (p-eIF2α) prevents ribosome assembly, which results in a translational block ... provides neuroprotection in ischemic stroke. The Role of Endoplasmic Reticulum ...

It is well known that inter-organellar communications play important roles in maintaining cellular homeostasis in response to environmental stresses. The endoplasmic reticulum (ER), extending ...

Ribosomes getting stuck The team also made an important discovery about ribosome collisions—where one ribosome runs into another due to a tricky RNA segment or differences in speed, for example ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins.

During translation, ribosomes can pause on the nucleic acid. Researchers showed that collisions from incoming proteins get them moving again. Shelby is an assistant editor for The Scientist. She ...

The ribosome is a large assembly of proteins and ribosomal RNAs (rRNAs) that functions to translate messenger RNAs (mRNAs) into proteins. The ribosome catalyzes the assembly of amino acids into ...

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug ...

Moreover, the study identified, for the first time, the fully rotated ribosome bound to the open form of eEF3. The researchers found that eEF3 binds to the ribosome early in translocation ...

Scientists have developed a breakthrough microscopy technique to observe ribosomes in action as they translate mRNA into proteins. This method revealed that ribosomes cooperate when encountering ...

Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ...