For both SLE and HD, CD138+ PC are at a higher frequency in BM than PBL. Expression of Ki-67 associates with the PBL compartment where it is found on all PC subsets regardless of CD19 or CD138 ...

Sickle cell disease (SCD) with concurrent systemic lupus erythematosus (SLE) is an uncommon but significant association requiring heightened clinical awareness, according to results from a ...

While there is variability between in vitro studies, SLE DCs exhibit an aberrantly mature and activated phenotype. Relationship Between Type I IFN & Dendritic Cells in SLE IFN-α is produced ...

Richardson et al. reported that CD4 + T cells were observed to increase self-reactivity when they were treated with a DNA methylation inhibitor, 5-azacytidine (6). Since then, a series of studies have ...

Obinutuzumab resulted in rapid and potent depletion of peripheral B cells without an increase in the incidence of serious adverse events, serious infections or death compared with placebo.

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...

Jan. 30, 2025 — A new study has highlighted the potential of resveratrol, a natural compound found in grapes, blueberries, and raspberries, to enhance female fertility. The systematic review ...