Ventura A Selective IgA deficiency was observed in 12 of 688 (1.7%) patients with celiac disease who were clinically undistinguishable from patients with celiac disease with normal IgA levels.
Immunoglobulin G (IgG) antibodies are a critical component of the adaptive immune system, binding to and neutralizing pathogens and other foreign substances. Recent advances in molecular antibody ...
You have full access to this article via your institution. Since our initial study, we have not found any additional TACI coding variants in 34 individuals with IgAD, as determined by genomic ...
Due to the autoimmune etiology of this disorder, IV immunoglobulin (IVIg) or plasma exchange (PE) are the first-line treatments in addition to management of ventilatory failure. IVIg is more ...
These include the selective translation of mRNAs encoding proteins that are engaged in tumour cell proliferation, growth, angiogenesis, response to mitogenic stimuli and the tumour ...
The aim was to investigate the influence of protein fragment format on the kinetics and extent of ocular penetration in vitro. Methods: Immunoglobulin single chain variable domain fragments of a ...
1. Swelling: A severe lack of protein, like in Kwashiorkor, causes fluid buildup, leading to swelling in the arms and legs. 8. Anemia: Protein plays a role in red blood cell production. A lack ...
In the clinical setting, a phase II trial (NCT02798496: CAPTIVE/KEYNOTE-192) evaluating the combination of DNX-2401 with the anti-PD-1 antibody pembrolizumab in patients with recurrent ... use ...
Indeed, developing such binders can be challenging. Small molecules like fentanyl do not bind major histocompatibility complex (MHC) molecules and so are not presented to T cells by MHC-bearing ...
In summary, experience to date supports the decision not to treat individuals with MHSA and normal liver function with nitisinone and dietary phenylalanine and tyrosine restriction. MAAI deficiency ...
Adults with type 2 diabetes using a GLP-1 drug have a similar risk for thyroid cancer as those using other diabetes drugs, though increased thyroid cancer risk was observed in the first year after ...