p53 is a transcription factor that regulates the expression of genes involved in tumor suppression. p53 mutations mediate tumorigenesis and occur in approximately 50% of human cancers. p53 regulates ...

The tumor suppressor p53 is activated upon multiple cellular stresses, including DNA damage, oncogene activation, ribosomal stress, and hypoxia, to induce cell cycle arrest, apoptosis, and senescence.

Background While p53 mutations occur early in Barrett’s oesophagus (BE) progression to oesophageal adenocarcinoma (EAC), their role in gastric cardia stem cells remains unclear. Objective This study ...

He scored the most clutch of touchdowns in the fourth quarter with a run into the end zone and then completely botched the spike of the football. It was ridiculously bad. PATRICK MAHOMES CALLED ...

New York Gov. Kathy Hochul has announced a new $77 million plan to clamp down on subway crime, while the MTA has also begun installing "spikes" on some of its turnstiles to stop fare evaders who ...

We may earn a commission from links on this page.

Mattel shares surged more than 15% after the toy giant said it’s weighing price increases for Barbie and other iconic brands because of President Trump’s tariffs on Chinese goods. The El ...

The Army attributed the spike in incidents to an "ineffective safety culture." Its aviation review called for more recording and reviewing of flight footage with superiors after it found that the ...

In December 2024, cases of HMPV drove spikes in respiratory illnesses in China, India and Malaysia, with China experiencing a surge in cases among children under 14. The upward trend was seen ...

It took a while, but Superficial is now Number One on the all-genre iTunes albums chart. The spike in downloads comes after Montag and her husband, Spencer Pratt, lost their home during the raging ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

Caroline joined the Live 5 News team in June 2024. Professional Experience: Last year, I was the news intern for WBRC Fox 6 and WVTM NBC 13 in Birmingham, AL. News Philosophy: As journalists, it is ...