Excitatory synapses are located in confined chemical spaces called the dendritic spines. These are atypical femtoliter-order microdomains where the behavior of even single molecules may have ...

A tiny brain for immense discoveries. The fruit fly, this simple vinegar fly, holds within it the secrets of neural connections. Could understanding its brain pave the way for insights into human ...

Scientists have uncovered a crucial pathway that links brain cell activity to the activation of genes responsible for ...

The post-synaptic side of the synapse is now recognized as a site ... which focuses on the cell biology of a number of ligand- and voltage-gated ion channels involved in post-synaptic ...

An electrical impulse cannot directly cross the gap so a different mechanism has to be used. Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ...

A multi-disciplinary team has found that depriving lab mice of sleep can lead to a reduction in synapse diversity in the brain. In their study, published on the open-access site Current Biology ...

The involved risk genes suggest an impairment of synapse biology, so the ability of neurons to communicate with each other. This impairment might also be present in the brains of schizophrenia ...

“Next, we are studying how to dynamically adapt these CAR T cells at the synapse level to make them more effective.” “Tumors are very sophisticated. We need to adapt our tools to the biology ...

the Dorys McConnell Duberg Professor of Neuroscience and Cell Biology at Yale School of Medicine and corresponding author of the study. The team found that these electrical synapses don't simply ...