This study investigated the role of TIPE2 in regulation of CD4 + T lymphocyte function in interaction of PHSML and TLR2/TLR4. Methods: The splenic CD4 + T cells were isolated from various mice (WT, ...

Through LPS-TLR4 the LPS-induced CB ligands-CB1 signaling pathways, pro-inflammatory macrophages also aggravate adipose tissue inflammation. Moreover, macrophages secrete the enzyme DPP4, which causes ...

The ECM (extracellular matrix) provides the microenvironmental niche sensed by resident vascular smooth muscle cells (VSMCs). Aging and disease are associated with dramatic changes in ECM composition ...

纤维化是损伤后细胞外基质（ECM）过度沉积的过程，会破坏多个器官的组织结构 ... 已有报道称，青蒿琥酯在脂多糖（LPS）刺激后可抑制巨噬细胞中的 Toll 样受体 4（TLR4）信号通路，这解释了青蒿琥酯在脓毒症模型中的保护作用。髓样分化蛋白 2（MD2）作为共 ...

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Engineered extracellular vesicles play an increasingly important role in the treatment ...

Situated in the Biomedicum building on KI Campus Solna, Richter-Dahlfors’ research group embraces scientists with expertise in micro­biology/infection ...

However, its application is limited due to various reasons. Nanotechnology, in the form of nanomaterials and nano-drug delivery systems, has been proven to increase the potency of active substances in ...