Marietta, GA, who make a pancreatic digestive enzyme product. The TIGAR-O classification system, which categorizes risk factors for chronic pancreatitis according to mechanism and prevalence ...

Furthermore, immunotherapy is not a great option either. While some tumors contain dormant immune cells called lymphocytes that may be awakened by checkpoint inhibitors, pancreatic cancer cells are ...

Preliminary safety, antitumor activity, and circulating tumor DNA (ctDNA) changes with RMC-9805, an oral, RAS(ON) G12D-selective tri-complex inhibitor in patients with KRAS G12D pancreatic ductal ...

Novel combination strategies are urgently needed to enhance efficiency of MWA. Conclusions: In this study, we found that the XIAP inhibitor AZD5582 modulates the immune microenvironment and inhibits ...

Pancreatic cancer is one of the deadliest of all cancers. Only 12% of men diagnosed with pancreatic cancer are alive five years after diagnosis; for women it is 14%. In pancreatic cancer, symptoms ...

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Although increased understanding of the molecular background to pancreatic cancer can certainly ... monoclonal antibodies, EGFR inhibitors, COX2 inhibitors and circumvention of hENT1 in ...

Pancreatic cancer is a highly lethal digestive malignancy with a 5-year survival rate of 10%. So far, the available therapeutic strategies are scarce and the few advancements made, as is the case of ...

These next-generation STAT6 inhibitors demonstrate excellent oral bioavailability, cell permeability, and metabolic stability, and do not target STAT6 for degradation. DeepCure expects to select a ...