Alzheimer's disease (AD) is a chronic neurodegenerative disorder that is characterized by memory and physical impairment in aged individuals. microRNAs (miRNAs) are small, single-stranded noncoding ...

The RISC, guided by the miRNA, binds to complementary sequences in the 3' untranslated region (UTR) of target messenger RNAs (mRNAs). This binding leads to translational repression or mRNA degradation ...

There are notable differences between men and women in their susceptibility to many human diseases, including cardiovascular ...

1 This means miRNA guides can target any mRNA with homology to its seed region, even if the rest of the sequence is not a match. This promiscuous binding activity means that miRNA can act on many ...

There have been 67 confirmed human bird flu cases in the U.S. since April 2024. Moderna has been awarded approximately $590 million from the federal government to help speed up the development of ...

This study presents a new prognostic model using mitophagy-related genes (MRGs) in glioma, a type of brain tumor, developed through bioinformatics. The model seeks to improve the understanding of ...

The Nobel Prize in medicine was awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA, molecules that help ...

It might seem strange that miRNA-loaded Argonaute proteins can inhibit ... a sequence-specific tag to deposit the machinery on the mRNA. It then becomes important to characterize the proteins ...

"MicroRNA is quite stable ... The recipes from DNA are carried by messengers called messenger RNA or simply mRNA. Does this sound familiar? Several of the COVID-19 vaccines used in Norway are ...