Mouse experiment. Image by tiburi via Pixabay Researchers at Queen Mary University of London have successfully integrated ancient genes into mouse cells, demonstrating that these primordial genetic ...

TASTPM is a double transgenic mouse model of Alzheimer’s disease carrying two mutations associated with early onset disease: the Swedish mutation in APP and the M146V mutation in PSEN1. The double ...

2015). The transgene expressed by these mice encodes mutant APP with the Swedish mutation (K670N/M671L) and the Austrian mutation (T714I) under the control of the Thy1.2 promoter. The parental origin ...

Methods: This study aimed to characterize the functional integrity of long white matter tracts in CADASIL transgenic mice, both with and without focal white matter lesions ... resting-state functional ...

A research group led by Wei Li at the Chinese Academy of Sciences has created mice born from two male parents and capable of reaching adulthood. This builds on previous work from the group in ...

A new research paper was published in Volume 16 of Genes & Cancer on January 20, 2025, entitled, "Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation.

This study investigates alterations in the autophagic-lysosomal pathway in the Q175 HD knock-in model crossed with the TRGL autophagy reporter mouse. The findings provide valuable insights ... with ...

To directly examine the interplay between mutant p53 or Mdm2 and wild type p53 in gene occupancy and expression, an integrated RNA-seq and ChIP-seq analysis was performed in vivo using isogenically ...

Here’s how it works. Having the best gaming mouse is just as vital to your PC gaming setup as your gaming PC or display. It might not make you a competitive esports player overnight, but it can ...

Using the best mouse can have a transformative effect on your overall PC experience. More than just a peripheral device, a decent mouse controls the ebb and flow of your workflow management ...