A 2023 report from the National Coffee Association found that 63% of Americans drink coffee every day. According to recent surveys, the ...

Adenosine receptors are G protein-coupled receptors that mediate the effects of adenosine, a purine nucleoside. There are four main types: A1, A2A, A2B, and A3, each with specific functions and tissue ...

Exploration of adenosine mechanism revealed adenosine receptors as a potentially useful target of therapy in RA.

School of Pharmaceutical Sciences, University of Geneva, 1206 Geneva, Switzerland Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva ...

The activation of the adenosine A2A receptor, which is mediated by the inhibition of adenosine A1 receptor, has been associated with depression-like behavior and anhedonia. High levels of cortisol, ...

Study of 2.4 million participants reveals potential advantages for cardiometabolic and psychiatric conditions alongside increased risks of gastrointestinal and musculoskeletal issues Study ...

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A new bridge built as part of a project to widen a section of the A1 has been found to have defects. The Allerdene Bridge, in Gateshead, was replaced by a new structure that opened in September ...

Adenosine signalling via the P1 purinergic receptors A1, A2A, A2B and A3 primarily exerts anti-inflammatory effects on immune cells and is either reduced when adenosine is hydrolysed to inosine by ...