ANY NOXIOUS, UNINTENDED & UNDESIRED EFFECT OF A DRUG WHICH OCCURS AT A DOSE USED IN HUMANS FOR PROPHYLACTIC, DIAGNOSTIC OR THERAPEUTIC PURPOSES. FDA Definition- Any ...

It should be noted that off-target binding of the drug could lead to ADRs and may ... Unavoidable ADRs are the idiosyncratic reactions for which the underlying mechanisms are not understood.

Adverse drug reactions (ADRs) remain a common clinical problem since they can mimic many diseases and cause significant morbidity and mortality. Judicious prescribing is important to minimize ...